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Corporate Governance

 
 
Group Structure and Shareholders
Capital Structure and Shares
Board of Directors
Management
Compensation, Shareholdings and Loans
Shareholders Participation
Changes of Control and Defense Measures
Auditors
Information Policy
Insider Policy
Ethical Business Conduct
 
 
 
Articles of Incorporation
Statuten D [371 kb]Code of Conduct
 

Group Structure and Shareholders

(December 31, 2009, unless otherwise noted.)

Group Structure

The Basilea group is composed of its parent company, Basilea Pharmaceutica Ltd. ("Basilea"), Basilea Pharmaceutica International Ltd. ("Basilea International"), the Swiss operating subsidiary, BPh Investitionen Ltd. ("BPh"), a subholding company, Basilea Pharmaceutica China Ltd. ("Basilea China"), a Chinese operating subsidiary held through BPh, and fully owned subsidiaries in Canada, Denmark, France, Germany, Italy, Spain, and the United Kingdom focusing on the distribution of pharmaceutical products (collectively the "Company").
 
The operating activities of the Company are focused on research, development and commercialization of pharmaceutical products. The Company’s operating activities are directed by and primarily located within Basilea International. Basilea International is operationally organized along core activities with Commercial Operations, headed by the Chief Commercial Officer, a Development function, headed by the Chief Medical Officer, a Research function, headed by the Chief Scientific Officer, Finance and Business Development, headed by the Chief Financial Officer and Technical Operations, headed by the Chief Technology Officer. These heads are members of the Management Committee. The Management Committee is led by the Chief Executive Officer. For further information on the Management Committee, please refer to the section "Management/Members, Functions and Other Activities".
 
Basilea is represented on the Board of Directors of its fully owned subsidiaries. In addition, there is a close cooperation related to the operations between Basilea International’s research, development and commercial groups and its subsidiaries.

Basilea Pharmaceutica Ltd.

Basilea is located at Grenzacherstrasse 487, 4058 Basel, Switzerland, and Basilea’s shares were listed on the SIX Swiss Exchange on March 25, 2004, under the Swiss security number (Valorennummer) 1 143 244. The ISIN is CH 001 143 244 7. The Common Code is 018859220. The ticker symbol is BSLN.
 
As of December 31, 2009, the market capitalization of Basilea amounted to CHF 617,748,158 (9,584,921 registered shares with a nominal value of CHF 1 per share). None of its shares were held by the Company on this date.

Basilea Pharmaceutica China Ltd.

Basilea China is a wholly foreign owned enterprise ("WFOE"), founded on May 29, 2002, and incorporated with limited liability under the laws of The People’s Republic of China, with a fully paid up registered capital of USD 7 million as of December 31, 2009. Basilea China is located in the Haimen Technological Development Zone, Jiangsu Province (north of Shanghai), People’s Republic of China. The subsidiary provides complementary services, primarily in the field of chemical synthesis research and development, in connection with Basilea’s research and development compounds. The shares of Basilea China are not listed on any stock exchange. All of its shares are held and controlled by BPh, a Swiss stock corporation with registered office at Zugerstrasse 76b in 6340 Baar, Switzerland. BPh has a share capital of CHF 131,950, divided into 10,150 fully paid-up registered shares with a par value of CHF 13 each, all held and controlled by Basilea.
 
As of December 31, 2009, the Company engaged more than 300 employees (full-time equivalents).
 
For information on the non-listed companies belonging to the Company, please refer to note 5 (Investments) to the Financial Statements of the Annual Report 2009.

Significant Shareholders

During the fiscal year 2009 and pursuant to the disclosure requirements of the Swiss Federal Act on Stock Exchanges and Securities (SESTA) Basilea published the following information regarding changes in the shareholder structure:
 
On January 12, 2009 UBS AG, Bahnhofstrasse 45/P.O. Box, 8098 Zurich, Switzerland, notified Basilea Pharmaceutica Ltd. that as of January 6, 2009 the shareholdings in Basilea Pharmaceutica Ltd. held by UBS AG, Bahnhofstrasse 45, 8001 Zurich, Switzerland, and its direct and indirect subsidiaries, with UBS International Holdings BV, Herengracht 600, 1017 CJ Amsterdam, Netherlands, (indirectly through UBS Holdings (France) SA, 65 Rue de Courcelles, 75008 Paris, France, indirectly through Caisse Centrale de Réescompte, 44 Rue Washington, 75008 Paris, France, indirectly through CCR Chevrillon Philippe, 4-6 Rond-Point des Champs-Elysées, 75008 Paris, France) and UBS Americas Inc., 2711 Centerville Road Suite 400, Wilmington 19808, Delaware, USA (indirectly through UBS Global Asset Management (Americas) Inc., The Corporation Trust Company, Corporation Trust Center, 1209 Orange Street, Wilmington 19801, Delaware, USA) and UBS (Luxembourg) S.A., 33a Avenue J.F. Kennedy, 1855 Luxembourg, Luxembourg, exceeded the thresholds of 3% and 5% pursuant to Art. 17 para. 1a SESTO-SFBC. The total holdings in Basilea Pharmaceutica Ltd. were 525,877 registered shares corresponding to 5.51% of the voting rights. The notification was published on the SIX Issuer Reporting Platform on January 14, 2009.
 
On January 13, 2009 UBS AG, Bahnhofstrasse 45/P.O. Box, 8098 Zurich, Switzerland, notified Basilea Pharmaceutica Ltd. that as of January 7, 2009, the shareholdings in Basilea Pharmaceutica Ltd. of UBS AG, Bahnhofstrasse 45, 8001 Zurich, Switzerland, and its direct and indirect subsidiaries, with UBS International Holdings BV, Herengracht 600, 1017 CJ Amsterdam, Netherlands, (indirectly through UBS Holdings (France) SA, 65 Rue de Courcelles, 75008 Paris, France, indirectly through Caisse Centrale de Réescompte, 44 Rue Washington, 75008 Paris, France, indirectly through CCR Chevrillon Philippe, 4-6 Rond-Point des Champs Elysées, 75008 Paris, France) and UBS Americas Inc., 2711 Centerville Road Suite 400, Wilmington 19808, Delaware, USA (indirectly through UBS Global Asset Management (Americas) Inc., The Corporation Trust Company, Corporation Trust Center, 1209 Orange Street, Wilmington 19801, Delaware, USA) and UBS (Luxembourg) S.A., 33a Avenue J.F. Kennedy, 1855 Luxembourg, Luxembourg, fell below the thresholds of 3% and 5% pursuant to Art. 17 para. 1a SESTO-SFBC. The notification was published on the SIX Issuer Reporting Platform on January 14, 2009.
 
On February 24, 2009 Basilea Pharmaceutica Ltd. received a notification of shareholdings from Fidelity International, Kingswood Fields, Millfield Lane, Lower Kingswood, Tadworth, Surrey KT20 6RB, United Kingdom, that FMR LLC ("FMR"), principal address located at 82 Devonshire Street, Boston, MA 02109, USA, and its direct and indirect subsidiaries, with FMR as the parent holding company of Fidelity Management & Research Company ("FMRCO"), investment manager for U.S. mutual funds, and Fidelity Management Trust Company ("FMTC"), a U.S. state chartered bank which acts as a trustee or investment manager of various pension funds and trust accounts as well as Pyramis Global Advisors Trust Company ("PGATC") and Pyramis Global Advisors LLC ("PGALLC") that are both indirect wholly-owned subsidiaries of FMR LLC reduced their holdings in Basilea Pharmaceutical Ltd. on February 20, 2009 to 279,497 registered shares corresponding to 2.92% of the voting rights. The notification was published on the SIX Issuer Reporting Platform on February 27, 2009.  
 
On February 25, 2009 Sectoral Asset Management Inc., 1000 Sherbrooke Street West, Suite 2120, Montreal H3A 3G4, Canada, notified Basilea Pharmaceutica Ltd. that Sectoral Asset Management Inc., as an investment advisor to several collective investment schemes for some of which Sectoral Asset Management Inc. also has the authority to vote on the shares held by the beneficial owners, increased its holdings in Basilea Pharmaceutica Ltd. on February 24, 2009 to 489,458 registered shares corresponding to 5.11% of the voting rights. The notification was published on the SIX Issuer Reporting Platform on February 27, 2009.
 
On March 9, 2009 Basilea Pharmaceutica Ltd. received a notification of shareholdings from Credit Suisse Asset Management Funds AG, Kalandergasse 4, 8045 Zurich, Switzerland, that it holds 290,594 shareholdings in Basilea Pharmaceutica Ltd. corresponding to 3.036% of the voting rights due to a securities lending pursuant to Art. 48 para. 2 SESTO-SFBC. The notification was published on the SIX Issuer Reporting Platform on March 11, 2009.
 
On March 11, 2009 Credit Suisse Asset Management Funds AG, Kalandergasse 4, 8045 Zurich, Switzerland, notified Basilea Pharmaceutica Ltd. that its shareholdings in Basilea Pharmaceutica Ltd. have fallen below the threshold of 3% on March 5, 2009 due to a securities lending pursuant to Art. 48 para. 2 SESTO-SFBC. The notification was published on the SIX Issuer Reporting Platform on March 12, 2009.  
 
On March 23, 2009 Basilea Pharmaceutica Ltd. received a notification of shareholdings from Credit Suisse Asset Management Funds AG, Kalandergasse 4, 8045 Zurich, Switzerland, that it holds 288,818 shareholdings in Basilea Pharmaceutica Ltd. corresponding to 3.018% of the voting rights due to a securities lending pursuant to Art. 48 para. 2 SESTO-SFBC. The notification was published on the SIX Issuer Reporting Platform on March 24, 2009.
 
On April 9, 2009 Credit Suisse Asset Management Funds AG, Kalandergasse 4, 8045 Zurich, Switzerland, notified Basilea Pharmaceutica Ltd. that its shareholdings in Basilea Pharmaceutica Ltd. have fallen below the threshold of 3% on April 6, 2009 due to a securities lending pursuant to Art. 48 para. 2 SESTO-SFBC. The notification was published on the SIX Issuer Reporting Platform on April 16, 2009.
 
On May 22, 2009 Basilea Pharmaceutica Ltd. received a notification of shareholdings from Credit Suisse Asset Management Funds AG, Kalandergasse 4, 8045 Zurich, Switzerland, that it has increased its shareholdings in Basilea Pharmaceutica Ltd. on May 18, 2009 to 288,115 registered shares corresponding to 3.01% of the voting rights pursuant to Art. 48 para. 2 SESTO-SFBC. The notification was published on the SIX Issuer Reporting Platform on May 26, 2009.
 
On May 26, 2009 Credit Suisse Asset Management Funds AG, Kalandergasse 4, 8045 Zurich, Switzerland, notified Basilea Pharmaceutica Ltd. that its shareholdings in Basilea Pharmaceutica Ltd. have fallen below the threshold of 3% on May 19, 2009 due to a securities lending pursuant to Art. 48 para. 2 SESTO-SFBC. The notification was published on the SIX Issuer Reporting Platform on May 27, 2009.
 
On June 12, 2009 Basilea Pharmaceutica Ltd. received a notification of shareholdings from Credit Suisse Asset Management Funds AG, Kalandergasse 4, 8045 Zurich, Switzerland, that it has increased its shareholdings in Basilea Pharmaceutica Ltd. on June 8, 2009 to 337,789 registered shares corresponding to 3.53% of the voting rights due to a securities lending pursuant to Art. 48 para. 2 SESTO-SFBC. The notification was published on the SIX Issuer Reporting Platform on June 13, 2009.
 
On June 17, 2009 Pictet Funds (LUX), 3, Boulevard Royal, 2449 Luxembourg, Luxembourg, notified Basilea Pharmaceutica Ltd. that Pictet Funds (LUX) – Biotech (subfund of Pictet Funds (LUX)) increased its holdings in Basilea Pharmaceutica Ltd. on June 12, 2009 to 496,891 registered shares corresponding to 5.19% of the voting rights. The notification was published on the SIX Issuer Reporting Platform on June 18, 2009.
 
On September 21, 2009 Basilea Pharmaceutica Ltd. received a notification of shareholdings from Fidelity International, Kingswood Fields, Millfield Lane, Lower Kingswood, Tadworth, Surrey KT20 6RB, United Kingdom, that FIL Limited ("FIL"), principal address located at Pembroke Hall, 42 Crow Lane, Hamilton, Bermuda, and its direct and indirect subsidiaries, with FIL as an investment adviser which provides investment advisory and management services to a number of non-U.S. investment companies or instrument trusts ("the International Funds") and certain institutional investors reduced its holdings in Basilea Pharmaceutica Ltd. on September 17, 2009 to 452,777 registered shares corresponding to 4.73% of the voting rights. The notification was published on the SIX Issuer Reporting Platform on September 23, 2009.
 
On October 7, 2009 Credit Suisse Asset Management Funds AG, Kalandergasse 4, 8045 Zurich, Switzerland, notified Basilea Pharmaceutica Ltd. that it has increased its shareholdings in Basilea Pharmaceutica Ltd. on October 1, 2009 pursuant to Art. 21 para. 1b SESTO-SFBC to 484,760 holdings corresponding to 5.07% of the voting rights. The notification was published on the SIX Issuer Reporting Platform on October 9, 2009.
 
On October 22, 2009 State of New Jersey Common Pension Fund D, PO BOX 290, Trenton, NJ 08625-0290, United States of America, notified Basilea Pharmaceutica Ltd. that its shareholdings in Basilea Pharmaceutica Ltd. have fallen below the threshold of 3% on October 7, 2009 and on that day amounted to 282'164 registered shares corresponding to 2.94% of the voting rights. The notification was published via the SIX Issuer Reporting Platform on October 23, 2009.
 
On November 5, 2009 Basilea Pharmaceutica Ltd. received a notification of shareholdings from Fidelity International, Kingswood Fields, Millfield Lane, Lower Kingswood, Tadworth, Surrey KT20 6RB, United Kingdom, that FIL Limited ("FIL"), principal address located at Pembroke Hall, 42 Crow Lane, Hamilton, Bermuda, and its direct and indirect subsidiaries, with FIL as an investment adviser which provides investment advisory and management services to a number of non-U.S. investment companies or instrument trusts ("the International Funds") and certain institutional investors reduced its holdings in Basilea Pharmaceutica Ltd. on November 4, 2009 to 284,195 registered shares corresponding to 2.97% of the voting rights. The notification was published on the SIX Issuer Reporting Platform on November 7, 2009.
 
On December 11, 2009 State of New Jersey Common Pension Fund D, P.O. BOX 290, Trenton, NJ 08625-0290, United States of America, notified Basilea Pharmaceutica Ltd. that it has increased its shareholdings in Basilea Pharmaceutica Ltd. on December 9, 2009 to 299,935 holdings corresponding to 3.13% of the voting rights. The notification was published on the SIX Issuer Reporting Platform on December 15, 2009.
 
On December 17, 2009 Credit Suisse Asset Management Funds AG, Kalandergasse 4, 8045 Zurich, Switzerland, notified Basilea Pharmaceutica Ltd. that it has decreased its shareholdings in Basilea Pharmaceutica Ltd. on December 11, 2009 to 477,812 holdings corresponding to 4.99% of the voting rights. The notification was published on the SIX Issuer Reporting Platform on December 19, 2009.
 
On December 17, 2009 Credit Suisse Asset Management Funds AG, Kalandergasse 4, 8045 Zurich, Switzerland, notified Basilea Pharmaceutica Ltd. that it has increased its shareholdings in Basilea Pharmaceutica Ltd. on December 14, 2009 to 481,388 holdings corresponding to 5.03% of the voting rights. The notification was published on the SIX Issuer Reporting Platform on December 19, 2009.  
 
Registered Shareholders

According to the share register, the shareholders shown on the following table held 3% or more of the shares and voting rights of Basilea as of December 31, 2009:
 
 

Shareholder
Number of 
registered shares 
Ownership
percentage
Chase Nominees Ltd., London
Wall 125, London WC2Y 2AJ,
United Kingdom
(registered without voting rights)
979 311
10.2
Pictet Funds Europe SA – Rub
Biotech, Boulevard Royal 1,
2449 Luxembourg,
Luxembourg
700 408
7.3
Roche Finanz AG,
Grenzacherstrasse 122,
4058 Basel, Switzerland
605 827
6.3
Varuma AG,
Aeschenvorstadt 55,
4051 Basel, Switzerland
395 000
4.1
State of New Jersey Common
Pension Fund D,
50 West State Street, Trenton, New Jersey 08625, USA
 
 
385 000
 
4.0
 
The numbers of shares and ownership percentages in the table above are given according to the share register report as per December 31, 2009, and take into account changes in share capital caused by the exercise of options during 2009. Further indications on significant shareholders are reflected in note 10 (Significant Shareholders) to the Financial Statements of the Annual Report 2009 pursuant to article 663c CO.  

Cross-Shareholdings

No cross-shareholdings existed as of December 31, 2009.

 

Capital Structure and Shares

Share Capital

The share capital of Basilea as of December 31, 2009, amounted to CHF 9,584,921 consisting of 9,584,921 registered shares with a par value of CHF 1 per share. The share capital is fully paid up. As of December 31, 2009, the Company did not hold any shares of Basilea.

Authorized Capital and Conditional Capital

As of December 31, 2009, total authorized capital amounts to CHF 2,000,000 and total conditional capital amounts to CHF 2,815,220.
 
On April 29, 2009, the ordinary shareholders’ meeting approved to extend the authorized capital in the amount of CHF 640,000 (640,000 registered shares with a par value of CHF 1 each), and approved additional authorized capital in the amount of CHF 1,360,000 (1,360,000 registered shares with a par value of CHF 1 each), both valid until April 29, 2011, which was entered into the Commercial Register of Basel-Stadt on the same day. The timing as well as the terms and conditions of the issuance of new shares are to be set by the Board of Directors. Newly issued shares must be fully paid up. The Board of Directors is entitled to exclude the preferential subscription right ("Bezugsrecht") of shareholders for the authorized capital in the amount of CHF 2,000,000 if the capital increase is made for strategic or financial purposes.  
 
Furthermore, shareholders approved to increase the conditional capital of up to CHF 2,828,738 (2,828,738 registered shares with a par value of CHF 1 each), to be fully paid up, in the ordinary shareholders’ meeting of April 29, 2009. CHF 2’188’738 of the conditional capital were reserved for the exercise of option rights granted under the Company’s stock option plan at a strike price to be set by the Board of Directors, and CHF 640,000 are reserved for the exercise of option or conversion rights granted to the holders of options or bonds in connection with new bonds or similar debt instruments that would be issued by Basilea or one of its subsidiaries, and for which the Board of Directors is entitled to set the conditions. The preferential subscription rights of shareholders are excluded under the conditional capital. The prior subscription right of shareholders ("Vorwegzeichnungsrecht") is granted for the portion of CHF 640,000, but its exercise is limited to three working days. The minimum issue price for shares issued in connection with bonds or similar debt instruments has to amount to at least CHF 75 per share. Relating to bonds or similar debt instruments connected with conversion or option rights for which the prior subscription right is withdrawn, the option rights may be exercised only during a maximum period of seven years, and the conversion rights only during a maximum of ten years.
 
In 2009 13,518 (2008, 27,725, 2007: 378,172) registered shares with a par value of CHF 1 per share were issued under the conditional capital in connection with the exercise of stock options under Basilea’s stock option plan.
 
Any shares issued under the authorized or conditional capital are subject to the transfer restrictions set forth under "Limitations on Transferability of Shares and Nominee Registrations").  

Changes in Capital

In 2009, Basilea increased its share capital by CHF 13,518 registered shares with a par value of CHF 1 per share) as a result of the exercise of stock options under the Basilea’s stock option plan.
 
In 2008, 27,725 registered shares were issued as a result of the exercise of stock options under Basilea's stock option plan.
 
In 2007, Basilea increased its share capital by CHF 1,380,000 (1,380,000 registered shares with a par value of CHF 1 per share) in connection with an offering to existing shareholders honoring the preferential subscription rights and in a global offering of the shares which had not been subscribed by existing shareholders. In addition, in 2007, 378,172 registered shares were issued as a result of the exercise of stock options under Basilea’s stock option plan.
 
For further information on changes in capital in 2009, 2008 and 2007, including changes in reserves and retained earnings, please refer to the Consolidated Statement of Changes in Shareholders’ Equity as well as note 13 (Shareholders’ Equity) to the Consolidated Financial Statements, and note 6 (Share Capital, Authorized Capital and Conditional Capital) to the Financial Statements of Basilea. Please also refer to the Consolidated Statement of changes in Shareholders’ Equity included in the Annual Reports 2008, 2007 for information on changes in equity in 2008 and 2007.  

Shares

Basilea has only one class of shares (registered shares) and the par value of Basilea’s shares is CHF 1 per share. Each share is fully paid up and carries one vote and equal dividend rights, with no special privileges.

Participation and Profit Sharing Certificates

Basilea has not issued any participation or profit sharing certificates.

Limitations on Transferability of Shares and Nominee Registrations

Basilea’s shares are not certificated since its IPO. Shareholders are not entitled to request printing and delivery of share certificates, but Basilea may, in its sole discretion, decide to print and deliver share certificates. Any shareholder may, however, at any time request Basilea to issue a confirmation regarding its shareholding, but such confirmation is not a negotiable instrument.  
 
The transfer of shares occurs through an entry in the books of a bank or depository institution following an assignment in writing by the selling shareholder and notification of such assignment to Basilea by the bank or the depository institution. It is planned to receive approval of the necessary changes of the Basilea Articles of Incorporation, which are required due to the coming into force of the FISA (Swiss Federal Act on Intermediated Securities) on January 1, 2010, at the Annual General Meeting scheduled for March 30, 2010.
 
A transfer of shares further requires that a shareholder files a share registration form in order to be registered in the share register of Basilea with voting rights. Failing such registration by the respective deadline set by the Board of Directors, a shareholder or usufructuary ("Nutzniesser") may not vote at, or participate in a shareholders’ meeting, but is still entitled to receive dividends and other rights of financial value. No exemptions were granted from the above restrictions in 2009.  
 
According to article 5 of Basilea’s Articles of Incorporation, a purchaser of shares will be recorded in Basilea’s share register as a shareholder or usufructuary with voting rights if the purchaser discloses its name, citizenship or registered office, respectively, and address, and gives a declaration that it has acquired the shares in its own name and for its own account. According to the nominee regulation enacted by the Board of Directors, a person or legal entity not explicitly stating in its registration request that it will hold the shares for its own account ("nominee") may be entered as a shareholder in the share register with voting rights for shares up to a maximum of 3% of the outstanding nominal share capital, provided such nominee enters into a nominee agreement with Basilea. Shares held by a nominee that exceed this limit are only registered in the share register with voting rights if such nominee declares in writing to disclose name, address, and shareholding of any person or legal entity for whose account the nominee is holding 0.5% or more of the outstanding nominal share capital. The limit of 3% shall apply correspondingly to nominees who are related to one another through capital ownership or voting rights or have a common management or are otherwise interrelated.  
 
Basilea’s Articles do not further limit the transferability of shares. A qualified majority of at least two-thirds of the share votes represented as well as the majority of the par values of shares represented at a shareholders’ meeting are required for resolutions on transfer restrictions of Basilea’s shares. For further information on the registration in the share register, please refer to the section "Registration in the Share Register".
 
Shares may only be pledged by written pledging agreement to the bank that administers the book entries of such shares for the account of the pledging shareholder. Basilea does not need to be notified of such pledging.

Convertible Bonds and Options

For information on the stock option plan for directors, management and employees, and on the number of options granted thereunder, please refer to note 12 (Stock-Based Compensation) to the Consolidated Financial Statements included in the Annual Report 2009.
 
As of December 31, 2009 there were no convertible bonds of the Company outstanding.

 

Board of Directors

Members, Functions and Other Activities

The following table sets forth the name and terms of the current members of the Board of Directors:
Name
Year of
first election
End of current
election period
Mr. Werner Henrich, Chairman
2000
2010
Mr. Steven D. Skolsky,
Vice-Chairman
2008
2011
Mr. Hans-Beat Gürtler
2009
2012
Prof. Daniel Lew
2003
2012
Mr. Claude Schreiner
2007
2010
Dr. Anthony Man
2004
2011
Mr. Ronald Scott
2004
2011
     Werner Henrich, Chairman
Anthony Man, CEO
 
 Steven D. Skolsky, Vice-Chairman
Daniel Lew
 
Mr. Werner Henrich

 
Dr. Anthony Man
Mr. Steven
D. Skolsky

 
Prof. Daniel Lew
 Claude Schreiner
Ronald Scott, CFO
Hans-Beat Gürtler
 
 
 
Mr. Claude Schreiner
Mr. Ronald Scott
Mr. Hans-Beat Gürtler

A description of each member’s nationality, business experience, education and activities is outlined below:

Werner Henrich, Chairman, was born in 1943 and is a French citizen. He has an education as a chemist and European patent attorney. He worked for F. Hoffmann-La Roche Ltd. ("Roche") in Basel for more than 30 years. Mr. Henrich held various positions at Roche including Head of Global Intellectual Property and Pharmaceutical Licensing for more than 12 years. He was also a member of the Roche Pharmaceutical Division Executive Board. In this function Mr. Henrich was responsible for intellectual property activities of all Roche divisions and for major pharmaceutical transactions including research collaborations, patent settlements, licensing-in and -out as well as product acquisitions. From February 2001 to October 2001, Mr. Henrich acted as CEO of Basilea. He retired from Roche in November 2003. Mr. Henrich has a wide experience in the pharmaceutical industry both with start-ups and large pharmaceutical companies. Mr. Henrich is also a member of the board of directors of Actelion Ltd., Allschwil and Addex Pharmaceuticals Ltd., Geneva, Swiss biopharmaceutical companies listed on the SIX Swiss Exchange. He acts as a consultant for several biopharmaceutical companies on a part-time basis.
 
Steven D. Skolsky, Vice-Chairman, was born in 1956, is a U.S. citizen, and holds a Bachelor of Arts degree in Biology from the University of North Carolina at Chapel Hill. Mr. Skolsky has over 28 years of general management and international pharmaceutical experience with emphasis on product strategy, commercialization and product development. He currently serves as the President and Chief Executive Officer of Sequoia Pharmaceuticals, a privately held U.S. based company specializing in novel antiviral therapeutics. Prior to his appointment at Sequoia, he held the position of Chief Executive Officer at Trimeris, Inc, a publicly held company that discovered and commercialized Fuzeon®, a novel, first-in-class HIV therapeutic in collaboration with partner F. Hoffmann-La Roche. Previously, Mr. Skolsky served over 23 years at GlaxoSmithKline in a range of senior leadership roles, including Senior Vice President, Global Product Strategy and Clinical Development, and Managing Director of GSK’s operations in Australia and New Zealand.
 
Hans-Beat Gürtler was born in 1946, is a Swiss citizen, and holds a Commercial Diploma. He currently serves as management partner for entrepreneurial investments of Varuma AG, a privately held Swiss investment company. He is Member and President of the Boards of Directors of several Swiss-based companies, most of them start-ups and SMEs, primarily in the pharma and biotech sector. Prior to joining Varuma, he held the position of Global Chief Executive Officer at Novartis Animal Health in Basel where he was responsible for the worldwide business, including research, development, manufacturing and marketing, of animal pharmaceuticals for pets and farm animals. Previously, Mr. Gürtler held various management positions at Ciba-Geigy Ltd., including business responsibilities in Eastern Europe, the Northern Hemisphere and the global pest-control business. As CEO of Mahissa, Ciba-Geigy's Seeds business in Spain, he lived in Barcelona for several years. 
 
Daniel Lew was born in 1948 and is a Swiss citizen. He is a Professor of Medicine at the University of Geneva Medical School and Chief of the Service of Infectious Diseases, Department of Internal Medicine at the Geneva University Hospitals. He obtained his MD degree from Geneva University in 1976 and specialized in infectious diseases both in Geneva and then subsequently at Harvard Medical School and Massachusetts General Hospital in Boston, Massachusetts, United States. He is a recipient of numerous scientific awards and grants for his research work. Professor Lew lectures widely, acts both as reviewer and editor for several major scientific journals, and is author of many publications on neutrophil function, bacterial pathogenesis and drug resistance.  
 
Claude Schreiner was born in 1942 and is a French citizen. He studied Economics at the University of Strasbourg (France) and has extensive experience in business and commerce. He started his career at Roche in 1966 and held various positions in the Pharma Division as well as in the Vitamins & Fine Chemicals Division at the Head Quarters in Basel. In 1978 he was appointed Head of the Vitamins & Fine Chemicals Division of Roche in France and subsequently General Manager of Roche’s main agrochemicals company, La Quinoléine S.A. In 1990, Mr. Schreiner became Head of the Roche Vitamins & Fine Chemicals Division for Western Europe and later General Manager of Roche France. In 2001 he took over as Head of Western European Pharma Operations and became a Member of the Roche Pharma Division Executive Committee. Mr. Schreiner has retired from Roche at the end of May 2007. 
 
Anthony Man, Chief Executive Officer, MD, FRCP, was born in 1956, is a Swiss citizen and holds an honor’s degree in biochemistry in addition to a medical degree. He is an elected Fellow of the Royal College of Physicians (UK). Dr. Man has over 20 years international pharmaceutical industry experience and has developed numerous successful products particularly in oncology. He has held a variety of senior positions spanning preclinical development to registration and commercialization while at Lederle, Roche, Ciba-Geigy AG, and Novartis AG. As Chief Development Officer at Basilea from 2001 to 2003, he built up the drug development organization and advanced all key development products through their major milestones. In April 2003, Dr. Man was appointed as Chief Executive Officer.  
 
Ronald Scott, Chief Financial Officer, was born in 1955 and is a Swiss citizen. Prior to joining Basilea, he worked for nine years at Roche in management positions in Pharmaceutical Finance, Licensing, and the Roche Corporate Finance Mergers and Acquisitions group. His assignments included managing Roche’s call, primary and secondary offerings on Genentech; Roche’s biotechnology investment portfolio; acquisitions and divestitures. Prior to joining Roche, Mr. Scott worked for Prudential Investment Corporation in the United States as director in Prudential’s Finance and International Business Development Units, managing divestitures and joint venture transactions.  
 
Dr. Man, CEO of Basilea, and Mr. Scott, CFO of Basilea, are executive members of the Board of Directors. Neither Dr. Man nor Mr. Scott is member of any of the Board Committees. All other members were non-executive board members in 2009.
 
Mr. Henrich, Chairman of the Board, acted as CEO of Basilea from February 2001 to October 2001. None of the other non-executive members of the Board of Directors served in the management of Basilea or any of its subsidiaries since inception of Basilea. In addition, Mr. Henrich acted as a consultant to Basilea in 2009.  
 
There are no other significant business connections between non-executive members of the Board of Directors and Basilea or any of its subsidiaries. For further information, please refer to note 18 (Related Party Transactions) to the Consolidated Financial Statements of the Annual Report 2009.  

Elections and Terms of Office

Basilea’s Articles provide for a Board of Directors consisting of between one and eleven members. Members of the Board of Directors are appointed and removed exclusively by shareholders’ resolution. Their term of office is up to three years, re-election being allowed. According to the Articles, elections are made by rotation in such a way that the term of office of about one third of the members of the Board of Directors may expire every year. The Chairman and the Vice-Chairman of the Board of Directors are designated by the Board of Directors.
 
According to the current organizational regulations of Basilea ("Organizational Regulations") enacted by the Board of Directors, each member of the Board of Directors shall resign effective as per the ordinary shareholders’ meeting immediately following completion of his or her 70th year of age, even if the term of office has not yet expired. Newly elected members enter into the term of their predecessors.  
 
Changes in the Board of Directors
Prof. Daniel Lew was re-elected as member of the Board of Directors for a term of three years, at the ordinary shareholders’ meeting on April 29, 2009. Dr. Andreas Wicki left his position as Vice-Chairman in order to fully focus on other tasks. The terms of Prof. Peter van Brummelen and Dr. Walter Fuhrer expired at the ordinary shareholder’s meeting on April 29, 2009 and they did not stand for another term of office. Mr. Hans-Beat Gürtler was elected as a new member of the Board of Directors subsequent to the ordinary shareholder’s meeting on April 29, 2009, Mr. Steven D. Skolsky was confirmed Vice-Chairman.  
 
For an overview of the years of first election and of expiry of the current terms of each member of the Board of Directors, please refer to the section "Board of Directors/Members, Functions and Other Activities".

Internal Organization and Areas of Responsibility

Responsibilities of the Board of Directors
The Board of Directors is entrusted with the ultimate direction of Basilea and the supervision of management. The Board of Directors’ non-transferable and irrevocable duties include to ultimately manage the corporation and to issue the necessary directives, to determine the organization, to organize the accounting system, the financial controls as well as the financial planning and to appoint, recall, and ultimately supervise the persons entrusted with the management and representation of Basilea. Furthermore, these duties comprise the responsibility for the preparation of the annual report and the shareholders’ meeting, the carrying out of shareholders’ resolutions and the notification of the judge in case of over indebtedness of Basilea.
 
In addition or specification of these duties, the Board specifically retains certain main decision-making competencies, including setting the strategy and short and long-term goals of Basilea; all M&A transactions as far as no shareholder approval is required; decisions on annual budgets; the general direction of research and development (e.g. therapeutic areas covered, areas of priority and third party co-operations); general policies in relation to personnel matters, including basic principles related to benefit and incentive plans; certain communication tasks towards shareholders and the public as required by applicable laws and regulations; and general policies on outsourcing versus internal functions for manufacturing, sales and marketing.  
 
According to the Organizational Regulations, resolutions of the Board of Directors are passed by way of simple majority. To validly pass a resolution, more than half of the members of the Board of Directors must attend the meeting. No quorum is required for confirmation resolutions ("Feststellungsbeschlüsse") and adaptations of the Articles in connection with capital increases pursuant to articles 651a, 652g and 653g of the Swiss Code of Obligations.  
 
Chairman of the Board of Directors
The Chairman of the Board calls, prepares, and chairs the meetings of the Board of Directors. The Chairman also chairs the shareholders’ meetings. He supervises the implementation of the resolutions of the Board of Directors and generally supervises the CEO and his Management Committee, who regularly reports to the Chairman on the meetings of the Management Committee and on all important matters of the Company. The Chairman is also entitled to attend the meetings of the Management Committee. In urgent matters that do not allow for the Board of Directors to take resolutions in time, the Chairman is entitled to take decisions that fall within the competencies of the Board of Directors. The Vice-Chairman of the Board of Directors exercises the powers of the Chairman in the Chairman’s absence.
 
Board Committees
The Board of Directors established an Audit Committee and a Compensation Committee in 2003. The tasks and responsibilities of these Committees are set forth in the Organizational Regulations. These Committees make proposals to the Board of Directors in their areas of responsibilities while the resolutions are passed by the Board of Directors. The Board determined to retain nomination responsibilities for the full Board of Directors.
 
In the meeting of the Board of Directors subsequent to the ordinary shareholder’s meeting on April 29, 2009, the following Audit Committee was elected or confirmed, respectively: Mr. Claude Schreiner (Chairman), Prof. Daniel Lew and Mr. Hans-Beat Gürtler.
 
Until April 29, 2009, the Audit Committee consisted of Dr. Andreas Wicki (Chairman), Prof. Peter van Brummelen, Dr. Walter Fuhrer, and Mr. Claude Schreiner, who were all non-executive members of the Board of Directors.
 
The Audit Committee assists the Board of Directors in fulfilling its duties of supervision of the management. It is responsible for the guidelines of Basilea’s risk management and internal control system, and the review of their adequacy and effectiveness, the review of the compliance, the assessment of the external auditors’ quality and work and the review of their audit plans, the monitoring of the independence of external auditors (including the authorizing of nonaudit services by the auditors and their compliance with applicable rules), the proposal of new auditors, if necessary, to the Board of Directors, the review of annual and interim financial statements, the review of the audit results, and the monitoring of the implementation of the findings by the Management Committee. The Audit Committee is at all times authorized to inspect the books and records of Basilea and to request information from and meetings with all management bodies and employees of Basilea as well as its external auditors. 

The Audit Committee held four meetings at the offices of Basilea in 2009, with a duration of approximately one half-day to a full day. The main topics at these meetings were the review of the year-end financial statements and Annual Report 2008; the review of the half-year financial statements 2009; the review of the annual budget 2010; financial and non-financial risk management and the scope of the external audit 2009. The external auditors were present at two Audit Committee meetings in 2009 to report on the results of the audit 2008 and the half-year review 2009. The respective recommendations of the Audit Committee were then further discussed for approval or modification by the full Board of Directors.
 
In the meeting of the Board of Directors subsequent to the ordinary shareholder’s meeting on April 29, 2009, the following Compensation Committee was elected or confirmed, respectively: Mr. Werner Henrich (Chairman), Mr. Claude Schreiner, Mr. Steven D. Skolsky and Mr. Hans-Beat Gürtler.
 
The Compensation Committee assists the Board of Directors in compensation-related matters. It provides the Board of Directors with recommendations on the compensation of the members of the Board of Directors and of the Management Committee, the policies for the compensation of the Management Committee and Basilea’s other employees, and the basic principles for the establishment, amendment and implementation of Basilea’s stock option plan.
 
The Compensation Committee held three meetings in 2009 each with a duration of one or more hours. The main topics at these meetings included the review of the 2008 achievements versus the planned Company objectives and determination of the performance-related bonus pool; the annual general salary increases; the grant of options; and the general remuneration of members of the Management Committee and employees. The respective recommendations of the Compensation Committee were then further discussed for approval or modification by the full Board of Directors.
 
Working Methods of the Board of Directors and its Committees
According to the Organizational Regulations, the Board of Directors must hold at least four meetings per year. When required, the Board of Directors holds ad hoc meetings or telephone conferences to discuss specific issues or passes resolutions by way of circulation.
 
In 2009, the Board of Directors held nine meetings with a typical duration of one-half to one day. Except for four meetings, all were held at the offices of Basilea. Three meetings were held by telephone conference. The overall attendance rate (in person or by phone) was more than 90%.
 
The members of the Management Committee report to the Board of Directors at each board meeting on the status of operations, especially related to the progress of clinical development, commercial operations and research programs as well as the status of drug supply and licensing activities. In addition, an update is given at board meetings on the status of the Company’s share price development.

The Board Committees report about their Committee meetings to the full Board of Directors at the board meeting following the relevant Committee meeting. Any resolutions on matters assigned to the Committees are taken by the Board of Directors on the basis of recommendations of the relevant Committee.
 
Responsibilities of the Management Committee
In accordance with the Articles and the Organizational Regulations, the Board of Directors has delegated all areas of management of Basilea that are not reserved by law, the Articles or the Organizational Regulations, to the Board of Directors (see section "Responsibilities of the Board of Directors"), to the CEO, and the Management Committee reporting to the CEO. The main duty of the CEO with the assistance of the Management Committee is to operationally manage the Company, to implement the strategies and other decisions of the Board of Directors, to make proposals to the Board of Directors regarding matters constituting decision making competencies of the Board of Directors, to set the operative focus and priorities as well as to procure the necessary resources.

Information and Control Instruments of the Board of Directors

The board meetings are the Board of Directors’ main platform to supervise and control the management. At each board meeting, the CEO and CFO report on the financial, business, research and development status, with a particular focus on the main risks of the Company related to its key value drivers, respective measures taken and related strategic proposals. The Board of Directors from time to time also calls upon further members of the Management Committee and management to attend board meetings for reporting purposes.
 
In addition, management provides interim updates to the Board of Directors as necessary on the status of operations and other issues that may be requested by the Board of Directors. The main components of these updates are the status of commercial operations, development and research programs as well as the status of the drug supply activities. Furthermore, management provides a monthly financial report to the Board of Directors including an unaudited consolidated balance sheet, profit and loss statement and statement of cash flows for the respective month. The financial report further includes comparisons of actual versus budget numbers.
 
The audited consolidated financial statements for the previous financial year are provided to the Audit Committee for their review at the end of January/beginning of February of each year. The consolidated interim financial statements for the half-year are provided to the Audit Committee at the end of July/beginning of August of each year. The financial statements are then recommended by the Audit Committee to the full Board of Directors at its subsequent meeting.
 
Furthermore, around November of each year, upon recommendation of the Audit Committee, the Board of Directors approves the annual budget of the Company for the following year. The Audit Committee reviews any budget changes as may occur from time to time related to strategic changes or opportunities. In the event the Audit Committee recommends any changes to the budget, the Board considers and may determine to approve such budget changes consistent with the strategy of the Company.
 
The Board of Directors additionally requests the auditors to issue a written report on any of their findings with respect to internal controls as a result of their audit procedures.

 

Management

(as of February 1, 2010)

Members, Functions and Other Activities

The Management Committee comprises certain executives including the CEO. Under the responsibility of the CEO and the supervision of the Board of Directors, it conducts the operational management of the Company pursuant to the Organizational Regulations and provides reports to the Board of Directors under the direction of the CEO at least on a monthly basis. Under the direction of the CEO, the Management Committee focuses on the corporate goals, budget, portfolio review and risk management, and as needed on organizational structure, corporate policies and corporate strategies. In addition, regular operational management meetings for the different functions are held. These operational management meetings, chaired by the responsible Management Committee member, mainly focus on significant operational issues concerning execution of goals, budget, resources, new business proposals, and priorities. The participants of these management operational meetings are key people on a managerial level, the CEO, and Management Committee members as required.
 
The following table sets forth the name, date of appointment and position of the current members of the Management Committee. In addition, a short description of each member’s nationality, business experience, education and activities is outlined below.  
 
Name
Appointed
Position
Dr. Anthony Man
2003
Chief Executive Officer
Dr. Ingrid Heinze-Krauss 2006 Chief Technology Officer
Prof. Achim Kaufhold
2010
Chief Medical Officer
Dr. Laurenz Kellenberger
2009
Chief Scientific Officer
Mr. Hans Christian Rohde
2007
Chief Commercial Officer
Mr. Ronald Scott
2000
Chief Financial Officer
 
 
Anthony Man, CEO
 
Ingrid Heinze-Krauss, Chief Technology Officer
 
Ronald Scott, CFO
Dr. Anthony Man
 
Dr. Ingrid Heinze-Krauss
 
Mr. Ronald Scott
 
 
 
 
 
Hans Christian Rohde, Chief Commercial Officer
  Laurenz Kellenberger, Chief Scientific Officer  
Achim Kaufhold, Chief Medical Officer
Mr. Hans Christian Rohde
 
Dr. Laurenz Kellenberger
 
Prof. Achim Kaufhold

For information on Anthony Man, Chief Executive Officer, and Ronald Scott, Chief Financial Officer, please refer to the section "Board of Directors" above.

Ingrid Heinze-Krauss, Chief Technology Officer, is a German citizen, holds a PhD in organic chemistry from the University of Freiburg, Germany, and was a fellow at the University of Massachusetts, USA. She joined Basilea in 2001 and built up the supply chain management group. Prior to joining Basilea she held a series of managerial positions in Pharma Research at Roche, including Area Head Medicinal Chemistry in Antibacterial Research and R&D project management.
 
Achim Kaufhold, Chief Medical Officer, a German citizen, holds a medical degree from the University of Cologne. During his 10-year academic career he worked in the fields of paediatrics, basic and applied medical microbiology, laboratory medicine and infectious diseases in Germany and the USA. Achim Kaufhold is Professor of Medical Microbiology and Infectious Diseases and a member of the Faculty of Medicine of the University of Aachen, Germany. Dr. Kaufhold has spent more than 16 years in senior management positions in the biotech and pharmaceutical industry, mainly in leadership roles in research, product and business development, and general management. During his industry career he was instrumental in the development, launch and life-cycle management of numerous products in many parts of the world, including Europe and the USA. Prior to joining Basilea, Dr. Kaufhold was President & Chief Executive Officer of Affitech A/S, previously Pharmexa A/S, Denmark. His previous senior management roles included CMO & Vice President of Development, Member of the Executive Committee at Chiron, now part of the Novartis group; CMO, Head of Research, Product & Business Development, Member of the Executive Committee at Berna Biotech, now a Crucell company; and Director Clinical Development & Head of the Pediatric Vaccines Development Unit at GlaxoSmithKline Biologicals with global responsibility for the development of the company´s  pediatric vaccine portfolio.
 
Laurenz Kellenberger, Chief Scientific Officer, a Swiss citizen, holds a PhD in organic chemistry from the Swiss Federal Institute of Technology Zürich (ETH Zürich). His scientific research continued at the University of Cambridge, UK and at Hoffmann-La Roche, Basel, Switzerland where he held different positions in preclinical research and chemical technologies before joining Basilea in 2000. Dr. Kellenberger’s expertise covers the range of synthetic organic and natural product chemistry to microbial molecular genetics. He is author of numerous scientific publications. At Basilea he held roles of increasing responsibility and served as Head of Chemistry and member of the research management team with responsibilities for key projects from lead finding and optimization through to preclinical development.  
 
Hans Christian Rohde, Chief Commercial Officer, Danish citizen, holds a Master of Science from the University of Copenhagen, August Krogh Institute, Sports Physiology and Education. In addition, he holds an MBA from the University of Birmingham. He has over 19 years of international experiences in the pharmaceutical industry. He has held operational and strategic positions in sales, marketing and general management across multiple therapeutic areas both in Europe and in the United States. His pharma and biotech experience was gained with Syntex Danmark A/S, Novo Nordisk A/S and Biogen Inc. Prior to joining Basilea he was Head of Global Therapeutic Area Reproductive Health with Merck Serono SA, Geneva, Switzerland.

Management Contracts

There are no management contracts between Basilea and any third parties.
 
For further information on activities for the Company and changes in the Management Committee, please refer to the sections "Board of Directors/Members, Functions and other Activities" and "Management/Members, Functions and Other Activities".

 

Compensation, Shareholdings and Loans

Content and Method of Determining the Compensation and Share Option Program

The compensation of the members of the Board of Directors and of the Management Committee is set and reviewed annually by the Board of Directors, based on recommendations of the Compensation Committee in accordance with Basilea’s compensation policies.
 
The compensation of the members of the Management Committee includes a base salary, as well as a bonus and stock options. The bonus and the stock options are based on personal and company performance. The bonus is calculated as a percentage of the base salary whereby the maximum is determined in the employment contract. The range of bonuses is between 25% and 40% of the base salary, whereby two members of the Management Committee have a guaranteed minimum bonus of 20% of their base salary provided that a bonus is distributed by Basilea. In addition, Basilea contributes to the pension plan and maintains certain insurances for death and invalidity.
 
The Board of Directors decides annually, considering the recommendations of the Compensation Committee, on the total amount of bonus to be granted based on the achievement of the Company goals set by the Board of Directors annually. These Company goals are related to the key value drivers of the Company, such as successful completion of clinical trials, providing drug supply for clinical trials, identification of clinical candidates, successful achievement of commercial operations goals and financing these activities. In a second step, the individual bonus for members of the Management Committee is determined by the Board of Directors upon recommendation of the Compensation Committee based on the individual performance and management’s respective contribution to achieving the Company’s goals.
 
The compensation of the members of the Management Committee and the members of the Board of Directors is reviewed yearly by the Compensation Committee. As part of this review, the Compensation Committee considers compensation packages at comparable companies in the industry based on the experience of the Committee members and publicly available information such that the Company remains competitive in its sector. This review forms the basis for the recommendation of the Compensation Committee to the Board.
 
The compensation package for non-executive board members consists of a fixed annual monetary compensation, a compensation based on meeting attendance and engagement in board committees as well as stock options. In addition, Basilea reimburses Director’s out-of-pocket expenses related to their engagement as members of the Board. The non-executive board members obtain a fixed annual compensation for their board membership of CHF 25,000. Furthermore, each non-executive board member obtains a meeting fee of CHF 5,000 per meeting attended whereby the maximum cumulated meeting fee paid per year is limited to CHF 25,000. In addition, each non-executive board member acting as a member of the Audit or Compensation Committee obtains an annual one-time committee fee of CHF 5,000. The Chairman of the Board of Directors receives a fixed annual compensation of CHF 37,500, an annual committee fee of CHF 7,500 and a meeting fee of CHF 7,500 per meeting attended whereby the maximum cumulated meeting fee paid is limited to CHF 37,500.
 
Executive members of the Board of Directors do not obtain any compensation for their participation in the Board of Directors. 

For further information on compensation and shareholdings, please refer to note 9 (Compensation and Shareholdings) to the Financial Statements of the Annual Report 2009.

 

Shareholders Participation

Voting Rights and Representation Restrictions

Voting rights may be exercised only after a shareholder has been recorded in Basilea’s share register ("Aktienbuch") as a shareholder or usufructuary ("Nutzniesser") with voting right. No exceptions from these restrictions were granted in 2009.
 
At shareholders’ meetings, shareholders can be represented by proxy by a third party who does not need to be a shareholder.
 
Subject to the registration of shares in the share register within the deadline set from time to time by the Board of Directors before shareholders’ meetings, Basilea’s Articles do not impose any restrictions on the voting rights of shareholders. Specifically, there is no limitation on the number of voting rights per shareholder. For further information on the conditions for registration in the share register (including in relation to nominees) and for attending and voting at a shareholders’ meeting, please refer to the sections "Limitations on Transferability of Shares and Nominee Registrations" and "Registration in the Share Register".
 
A shareholder resolution with a qualified majority of at least two-thirds of the share votes represented as well as the majority of the par values of the shares represented at a shareholders’ meeting are required for the creation of shares with privileged voting rights.

Statutory Quorums

There is no provision in the Articles requiring a quorum for shareholders´ meetings.
 
According to article 11 of the Articles, resolutions generally require the approval of the absolute majority ("absolutes Mehr") of the share votes represented at the shareholders’ meeting. Shareholders’ resolutions requiring such a majority include amendments to the Articles (subject to the exceptions below), elections of members of the Board of Directors, elections of the auditors and the group auditors, approvals of the annual report, the annual financial statements and consolidated financial statements of the Company, decisions regarding dividends, decisions to discharge the members of the Board of Directors and the management from liability for matters disclosed to the shareholders’ meeting, and the ordering of an independent investigation into specific matters proposed to the shareholders’ meeting ("Sonderprüfung").
 
Pursuant to article 12 of the Articles, a resolution passed at a shareholders’ meeting with a qualified majority ("qualifiziertes Mehr") of at least two-thirds of the share votes represented as well as the majority of the par values of the shares represented at a shareholders’ meeting are required for: (i) changes in Basilea’s purpose; (ii) the creation of shares with privileged voting rights; (iii) restrictions on the transferability of registered shares; (iv) an authorized or conditional capital increase ("genehmigte oder bedingte Kapitalerhöhung"); (v) an increase of capital out of equity ("Kapitalerhöhung aus Eigenkapital") against contributions in kind ("Sacheinlage") or for the purpose of an acquisition of assets ("Sachübernahme") and the granting of special benefits; (vi) the limitation or withdrawal of preferential subscription rights; (vii) the change of the registered offices of Basilea; and (viii) the dissolution of Basilea without liquidation (e.g. through merger). In addition, amendments of the clauses of the Articles of Basilea on transfer restrictions, on the conversion of registered shares into bearer shares as well as amendments to the clause relating to such additional items requiring a qualified majority also require the qualified majority mentioned before.
 
The shareholders’ meeting may at any time convert registered shares into bearer shares or bearer shares into registered shares through an amendment of the Articles.

Convening of Shareholders´ Meetings and Agenda Items

The shareholders’ meeting is the supreme institution of Basilea. Under Swiss law, the ordinary shareholders’ meeting takes place annually within six months after the close of the business year. Shareholders’ meetings may be convened by the Board of Directors or, if necessary, by the auditors. The Board of Directors is furthermore required to convene an extraordinary shareholders’ meeting if so requested in writing by holders of shares representing at least 10% of the share capital of Basilea, setting forth the items to be included on the agenda and the proposals. Shareholders representing shares with a par value of at least CHF 100,000 have the right to request in writing that an item be included on the agenda of the next shareholders’ meeting, setting forth the item and the proposals. According to article 7 of the Articles, the request to put an item on the agenda has to be made at least 45 days prior to the shareholders’ meeting. Extraordinary shareholders’ meetings can be called as often as necessary, in particular, in all cases required by law.
 
Shareholders’ meetings must be convened by publishing a notice in the Swiss Official Gazette of Commerce ("Schweizerisches Handelsamtsblatt") at least 20 days prior to such meeting. In addition, holders of registered shares may be informed by a letter sent to the address indicated in the share register.

Registration in the Share Register

The Board of Directors determines the relevant deadline for registration in the share register giving the right to attend and to vote at the shareholders’ meeting ("Stichtag"). Such deadline is published by Basilea in the Swiss Official Gazette of Commerce and the Company’s website, usually in connection with the publication of the invitation to the shareholders’ meeting. In case that such deadline for the ordinary annual shareholders’ meeting is already determined by the Board of Directors prior to the printing of the Annual Report, it will also be included in the Annual Report.
 
In 2009, the deadline for registration in the share register in order to participate and to vote at the ordinary shareholders’ meeting of April 29, 2009, was April 16, 2009. It is Basilea’s intention regarding future shareholders’ meetings that this timeframe will not change significantly.
 
The registration deadline for the ordinary shareholders’ meeting to be held on March 30, 2010, has been determined to be March 18, 2010.
 
Basilea has not enacted any rules on the granting of exceptions in relation to these deadlines.
 
For further information on the registration in the share register, please refer to the section "Limitations on Transferability of Shares and Nominee Registrations" above.
 
  

Changes of Control and Defense Measures

Duty to Make an Offer

The Articles contain no provision which would rule out the obligation of an acquirer of shares exceeding the threshold of 33 1/3% of the voting rights to proceed with a public purchase offer (opting-out provision pursuant to article 22 para. 2 and 3 SESTA), or which would increase such threshold to 49% of the voting rights (opting-up provision pursuant to article 32 para. 1 SESTA).

Clauses on Changes of Control

Basilea’s stock option plan contains provisions in respect of changes of Basilea’s shareholder base. The change of control definition in the stock option plan includes the launch of any offer for the shares of the Company, which meets or exceeds the mandatory offer threshold of 33 1/3% of all shares of the Company, if such offer becomes unconditional (subject to conditions subsequent).
 
In case of a change of control, all unexercised stock options of all option holders, including, but not limited to stock options held by members of the Board of Directors and of the Management Committee, vest and become exercisable.
 
In this case, Basilea will endeavor to provide for a cashless exercise and provide for the difference in the share price realized in such cashless exercise and the price offered for the underlying shares. Alternatively, Basilea will procure that the offeror will offer to purchase the options.  
 
Furthermore, upon a change of control, the provisions of the stock option plan cannot be changed to the detriment of their holders and Basilea will hold the option holders harmless for any income taxes or social security contributions that are due or may become due related to the exercise, conversion or sale of stock options. These provisions would also apply to stock appreciation rights under Basilea’s stock option plan.
 
In addition, with regard to all employment agreements of indefinite nature, the period for terminations for any cause by the Company, will automatically and immediately be extended to 12 months. In the event of any material change of the particulars of the contract regarding the position and location, the employee shall have the right to terminate employment with immediate effect resulting in a severance payment of an annual salary by the Company. Material change means a planned downgrading of more than one level in terms of position. In terms of work place, any location outside the greater Basel area is considered material.
 
No other change of control provision exists for the benefit of members of the Board of Directors or of the Management Committee.
 
 
 

Auditors

Duration of the Mandate and Term of Office of the Lead Auditor

The statutory and group auditors of Basilea are PricewaterhouseCoopers AG, Basel, Switzerland. PricewaterhouseCoopers AG has held the function of statutory auditor since inception of Basilea on October 17, 2000, and acts as group auditor since 2002. The lead auditor of Basilea since inception of Basilea up to the shareholders’ meeting in March 2008 has been Mr. Ralph R. Reinertsen. After seven years as lead auditor, Mr. Ralph R. Reinertsen rotated-out in 2008. The lead auditor of Basilea since March 2008 is Mr. Thomas Brüderlin.

Auditing Fees

In 2009, PricewaterhouseCoopers AG and its affiliates charged the Company auditing fees in the amount of CHF 218'173.

Additional Fees

In 2009, PricewaterhouseCoopers AG and its affiliates have not charged the Company any additional fees.

Control Instruments of the Auditor

The Audit Committee of the Board of Directors assumes the task of supervising the auditors. The Audit Committee meets with the external auditors at least once a year to discuss the scope and the results of the audit and to assess the quality of their services.  
 
In 2009, the Audit Committee met with the auditors twice to discuss the scope and results of their year-end audit for 2008, the scope of the 2009 audit as well as the results of their review of the half-year financial statements per June 30, 2009.
 

 

Information Policy

Basilea publishes financial results twice a year in form of an Annual Report and a Half-year Report (Interim Report). In addition, Basilea informs shareholders and the public regarding the Company’s business through press releases, conference calls and roadshows. Where required by law or Basilea’s Articles of Incorporation, publications are also made in the Swiss Official Gazette of Commerce.
 
The Annual Report is usually published within three months after the end of the financial year, and no later than April, while the Interim Report is usually published within two months after the end of the half-year reporting period. In addition, key financial figures for the respective reporting period are disclosed in a press release. Both, report and press release are usually published on the same day. The intended release dates for the Annual and Interim Report will be posted on Basilea's website (www.basilea.com) at the end of the respective full or half-year reporting period.
 
The Annual Report may be sent in printed form to all registered shareholders. Annual Reports, Interim Reports and press releases can be obtained free of charge in either German or English language versions upon request and are also made available on the Company’s website.
 
Basilea's website is the permanent source of information for investors and stakeholders. It also provides information on the Company’s research and development programs as well as contact information. In addition, it includes a corporate calendar with information on events important to investors such as the annual shareholders' meeting, conferences or analyst events. The corporate calendar is continuously updated throughout the financial year.
 
The Company will provide general guidance to enable the investment community and the public to better evaluate the Company and its business prospects for future performance. The Board of Directors has issued a disclosing policy to ensure that the investors will be informed in compliance with the requirements of the SIX Swiss Exchange.
 
The Company’s investor relations department is available to respond to shareholders’ or potential investors’ queries under investor_relations@basilea.com or via post at Basilea Pharmaceutica Ltd., Investor Relations, P.O. Box, CH-4005 Basel, Switzerland.
 
Additionally, investor relations inquiries may also be made by phone at +41 61 606 1233.
 
A subscription service to Basilea's press releases is provided at http://www.basilea.com/Investor-Relations/News-subscription.

 

Insider Policy

The Board of Directors issued an insider policy, which was reviewed and amended in 2006 in order to prevent insiders from benefiting from confidential information. The policy defines guidelines on how to deter corporate insiders from making use of confidential information. The Board of Directors has established close periods to prevent insiders from trading during sensitive periods.

 

Ethical Business Conduct

The Company is committed to the highest standards of ethical business conduct. As a biopharmaceutical company, the Company is operating in a highly regulated business environment. Strict compliance with all legal and health authority requirements, as well as requirements of other regulators, is mandatory. The Company expects that its employees, contractors and agents ("Personnel") observe the highest standards of integrity in the conduct of Company’s business. The Code of Conduct sets forth Company’s policy embodying the high standards of business ethics and integrity required of all Personnel when conducting business affairs on behalf of the Company. The Company is committed to complying with the spirit and letter of all applicable laws and regulations where the Company engages in business.
 
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